Wednesday, 10 February 2016

Technological advancements in catheters devices & cost-effectiveness to boost the market growth

You must have come across urethral catheterization as a routine medical procedure which facilitates direct drainage of the urinary bladder from the bladder into a bag along a tube or continuous pipe. Painful as it may seem, this procedure is essential for patients across all groups, mostly to help them to relieve urine because of their inability to pee. Known as urinary catheter, it is a type of medical catheter, used for different diagnostic purposes or to serve various therapeutic ends such as to relieve urinary retention, instill medication, or provide irrigation. Medical catheters are tubes–of varying diameter and flexibility–used in healthcare to deliver medications, fluids or gases to patients and to drain bodily fluids such as urine. They may be made up of plastic, silicon rubber, PVC and nylon and includes neurovascular Catheters, intravenous catheters, urinary catheters and chest drainage tubes. Of these, silicone is the most commonly chosen material due to its inertness as it does not react with body fluids.

Catheterization is considered as a primary co-procedure along with other medical procedures such as angioplasty, cardiac electrophysiology, and neurosurgery and others. Increasing cardiovascular diseases and rising demand for minimal invasive surgeries, the rising incidence of diabetes, urinary bladder failure, kidney failures along with major technological enhancements in the equipment which can relief pain are the factors that will foster the growth of the market. 

Technical advancements and other developments in the technology used to insert these catheters may be useful in instances of long-term administration of medications such as antibiotics in patients. Or, simply such enhancements in designing equipment may be popular driven by relieving pain in patients. A recent development earlier this year shows the adductor canal catheter has claimed to lower pain among patients following total knee arthroplasty (TKA). This has been confirmed through the results conducted by researchers from Philadelphia's Thomas Jefferson University hospital.

Companies manufacturing tubing used in catheter develop innovative evolving requirements of medical catheters and devices to keep up with evolving trends of medical catheters and devices. Putnam Plastics Corp. Dayville, Conn., pioneering in extrusion technologies for medical catheters and devices, has developed an advanced tri-layer tubing technology with improved tensile and burst strength, with reduced elongation properties. The new Super-Tri tubing helps in the prevention of wire lock-up in catheters which involves guidewires. The tubing utilizes the material combination similar to traditional tri-layer tubing while offering superior performance characteristics. The tri-layer tubing is mostly used in PTCA (percutaneous transluminal coronary angioplasty) delivery systems and involves a HDPE inner layer for lubricity, thus providing a unique combination of strength, bondability and trackability.

 Another Ohio-based manufacturer PercuVision LLC that deals mostly with developing high-end urinary catheters claimed it has sold its visually guided catheter-placement system to as many as 20 smaller rural hospitals over the past two years since it received federal approval to market the equipment. Since then, the company is also engaged in developing advanced versions for other medical procedures, such as inserting a feeding tube through the nose that may be camera-equipped. The company opines that offering visually guided camera-equipped catheter will lead to less complication and cost savings. Led by such developments, the opportunities for catheters market. As per a recent report by Allied Market Research, the market would reach $42.5 billion by 2020, registering CAGR of 7.5% during the forecast period of 2014-2020.

Thursday, 4 February 2016

Incandescent Light Bulb Getting Resurrected: A Recent MIT Research Suggests

Can government laws and bureaucratic set-up predict what free scientific and technological progress can or cannot achieve? The recent Wikipedia page titled “Phase-out of incandescent light bulbs” seems to suggest so. But why only Wikipedia: a plethora of recent media reports point to this direction that reiterates on the “death” of these bulbs, banned by governments in developed nations and discouraged by others. Many phase-out regulations that is being talked about in these reports relate to ban in the manufacture, importation or sale of incandescent light bulbs for general lighting purposes. As per a recent phasing out effort by EU, halogen bulbs have been phased out, and any bulb available for purchase after the 2016 date must have at least a B energy rating and these are to be replaced by Compact fluorescent lamps (CFL) and Light-emitting diode lamps (LEDs). Most European countries such as Brazil, Venezuela and Australia have already introduced a phase-out or ban. The reasons cited are attaining energy efficiency in general in all its electric components such as televisions & washing machines to tiniest motors and achieving a bigger goal E.U. goal of cutting greenhouse gas emissions by 20 % by 2020. They also put forth the argument that no noticeable improvement in incandescent efficiency in the last 10 years.

However, the recent claim by a team of researchers at MIT point otherwise. The incandescent bulb is being resurrected! Incandescent light bulbs works by the conversion of the electric current to heat energy which gets converted to light in the form of electromagnetic radiation. The emitted light contains the waves of all frequencies, especially those within the interval of the visible spectrum. Some of the frequencies are "not relevant" like the infrared waves and do not contribute our visibility. So, more than 95 % of the energy that goes into them is wasted, most of it as heat energy. Now researchers at MIT and Purdue University have decided to circumvent this problem.

New data center cooling systems to focus on energy efficiency

Data centers is a centralised facility for an organization’s IT operations and equipment where it stores, manages and disseminated its data and information concerning the functioning of the daily operations of the organisation or any particular business process. Data centers consist of network’s most critical systems and it is crucial that these data centers must remain cool so that the processors can function effectively and efficiently. To achieve this purpose of cooling, there must be a provision for effective data centers cooling system which would prevent the loss of data and discontinued flow of information thereby hindering the day to day business operations.

The exponential growth of data both structured and unstructured along with the continuing adoption for cloud computing is a key factor driving the demand for setting massive data centers. This would obviously require efficient and power-friendly data center cooling systems. Over the decade, there has been innovation in data center cooling, with large operators trying to achieve energy efficiency in their design of data center cooling systems.

Tuesday, 2 February 2016

Biomaterials (Bio Implants) Market - Market Dynamics, Opportunities & Forecasts.

Allied Market Research has recently introduced a report titled “Biomaterials (Bio Implants) Market - Opportunities and Forecasts, 2014 -2020”. The report offers an in-depth insight into key drivers and restraining factors, market challenges, key segmentation on the basis of materials, application across geographies along with the profile of key market players.

Biomaterials are natural materials which are artificially derived and have large medical applications for the purpose of organ transplantation and replacement of tissues. The report highlights how the market for medical devices which accounted $240 billion in 2013 point to huge growth prospects of the bio-implants market. Increasing count of aging population across the world is a key driver for biomaterial market driven by increased applications of biomaterial is increasingly being used in wound healing, surgery, dental implants, neurology and tissue engineering. As per an estimate by the Society for Biomaterials, over 5000 novel research article are published every year for newer and innovative wound care techniques and surgical devices. 

The report takes into account the potential growth opportunities of the key segments, impact analysis of top impacting factors, Porter’s Five Forces Analysis along with identifying top investment pockets using the strategic tool such as GE9 cell matrix analysis. The report offers key developmental strategies adopted by key market players which would provide in-depth understanding of potential opportunities and market challenges faced by prominent companies. The analysis is expected to offer an unbiased assessment of industry value chain and factors that will create potential growth prospects for top companies. 

This report considers the competitive analysis of key market players. Top companies have collaborated to consolidate their positions in biomaterial market. For instance, Wright Medical Group recently completes the acquisition of BioMimetic Therapeutics Inc. which will help Wright’s Extermities business to expand its product portfolio by taking advantage of BioMimetic's cutting-edge biologics platform.

The report is aimed to key audiences such as medical device manufacturing companies, pharmaceutical companies, R&D institutes and academic institutes and other interested stakeholders.



Monday, 1 February 2016

Regenerative Medicine explore new therapies using stem cells research & nanotechnology

Regenerative medicines and associated therapies can help mammalian cells to reconstruct: reconstruction of lost limbs, human cells, tissues and tendons, or even undo organ problems. Regenerative medicines have emerged as a promising field of tissue engineering and refers to the practice of providing treatments to repair, regenerate, and replace damaged cells and tissue. The numerous applications include offering therapies for complex diseases such as Alzheimers and spinal injuries or providing cures for chronic ones like cancer and diabetes. The trend of restoring damaged tissues is evident in spray-on skin and lab-grown ears, with the terms tissue engineering and regenerative medicine used interchangeably.



The benefits of regenerative medicines seemingly extend over medical applications to non-therapeutic ones such as biosensors which are employed to detect biological or chemical threat agents, or biomaterial chips that can assess the toxic effects of a medication. One of the main goals of this emerging field is to improve people’s quality of life and restoring them back to a normal functional state.

Researchers world have already been experimenting with stem cells for long. These progenitor cells can develop into several types of tissue, thereby driving the bodies to heal themselves. Some of the early and most promising clinical trials involved treating congestive heart diseases and regrowing muscles in soldiers who were severely wounded in war. Advances in stem cells especially related to pluripotent cells to treat various regenerative disorders focuses on stem cells that can turn into any kind of cell and is a key factor triggering the growth of the regenerative medicines market.

See related Press Release: http://goo.gl/aHFjeB

Regenerative medicines evolving as a multidisciplinary field of biomaterials incorporates nanotechnology as a potent tool to produce material structures that mimic the biological ones capable of providing very efficient delivery systems. The fabrication of materials, such as nanoparticles and scaffolds used for tissue engineering, and the nanopatterning of surfaces can help get “in vivo” in response to the biological signals mammalian cells receive from the surroundings. The applications of stem cells to harness the power of regenerative medicines for curing diseases such as frontotemporal dementia and amyotrophic lateral sclerosis (ALS) look for collaborative findings to help researchers to discover new approaches. Last month, two collaborative teams within USC Stem Cell bagged an award Audrey E. Streedain Regenerative Medicine Initiative Awards. The magnanimous award which summed up to $140,000 each support faculty members affiliated to USC who is keen on multi-investigator research collaborations with the goal of curing diseases using stem cells as potent tools. The eminent researchers Justin Ichida and Paula Cannon, with Department of Stem Cell Biology and Regenerative Medicine, aim to develop a powerful technique for which can help to rectify a gene mutation responsible for 10 % of all cases of ALS & frontotemporal dementia . According to Cannon “These grants are pretty unique in that they allow the type of high-risk research that isn’t feasible without collaboration,”

Various alliances have cropped up recently this year that hope to the bridge the gap between the academia and industry so that the ongoing R&D activities can translate to effective patient care using regenerative medicine. 

The Rare Disease Clinical and Patient Education Roundtable which took place on  27th January in Washington is focused on educating multi-sector stakeholders regarding the growth prospects of regenerative medicine market and large scale applications to cure various rare diseases. The event, first of its kind, is announced by the Alliance for Regenerative Medicine (ARM), an international organization representing the researches on gene therapy, cell therapy and tissue engineering. Such collaborations and joint events will tend to increase in future, as the technology progresses and results of cutting-edge research and clinical trials are made public. No doubt, dominant strategy adopted by companies is approval required to initiate clinical trials, continuation of trials and for the commercialization of these therapies. As per a recent report by Allied Market Research gene therapies are expected to be the fastest emerging technology, growing at a CAGR of 28.6% during 2014-2020 forecast period.  

Tuesday, 13 October 2015

Competition in Craft Beer Market Strengthens Marketing Strategies

Each beer admirer has an onelist interpretation when trying to detail craft beer and tales of discovery to share. Defining a true craft beer becomes more difficult with each beer brand offering something new. Going over-board many craft beer manufacturers are bringing consumers into their marketing sphere. Brewers making customers feel like they are naturally discovering their beer, is worth a toast. Craft beer is a billion-dollar business today where off -strategy sale and marketing was unwelcomed so far as a pint of Natural Beer (rated as world's worst beer by Refinedguy.com in 2013) So how do craft beer makers anticipating growth apply as well as execute compelling marketing strategy?



How effective business plans unfold without adulterating reliability and tarnishing customer relationship? Marketing for craft beer apes’ small business enterprise as well as retail marketing. Besides this there is a lot more fun when integrated with social media like Facebook, Twitter, Instagram and more into the mix! Several studies indicate that craft beer represents just close to 6% of the entire beer industry, but the market is continuously pouring on many beer lovers. Craft drinkers today keep a tab and follow their preferred market on media to know the beers they got to try! Such social media strategy and follow function has enabled craft beer bars to stay more competitive than their rivals.



Another factor that has guided several craft breweries like Meg Gill and Tony Yanow based in Los –Angeles is wholesale beer distributorship. Many parts of the United States were earlier not very receptive to this beer category. The competition between the small craft breweries have heated up, and what’s more important is how different brands are defining the drinking experience beyond the can or bottle. Hosting or attending beer events has helped producers expand their presence and grow their customer base. For the inside scoop on how healthy are craft beers, we picked the below chart. 



So why is there so much of hype for craft beer marketing? Many answer because the entire world has woken up to different flavors and savor in everything and beer forms an important part. In an interview to CNBC’s, Closing Bell Founder and Brewer at Boston Beer Jim Koch said when began brewing in his kitchen almost thirty-one years ago, many did not appreciate his idea. He added, but now Americans have started demanding both quality and taste in their beer. Several researches reveal that in America alone the number of craft beers have almost doubled in size (between 2014 – 2015). By the end of 2015, experts indicate that there would be new breweries opening up in the country every 10 or 12 hours. Industry growth is increasing in different countries such as America, Australia etc. and steaming from the blend of provenance including retail environment and effective business models. 

Furthermore, the continuous growth of independent breweries demonstrates that increasing industry opportunities and demand are widespread. So with competition in the sector growing the need for producers to be able to differentiate and brew world-class beer has become more important than ever. The growth is likely to accelerate through the progress of tax breaks for breweries in countries like Australia. Small businesses have now emerged as of the intense spots in both a country’s economy as well as culture. Craft brewers are fulfilling the demand of their local communities, brewing up fresh jobs and encouraging tourism. New craft brewers who match standards like high quality have been welcomed by customers across the world with open arms. 


There has been a significant growth in the session beer that has not only allowed the existing craft beer lovers to increase the volume but also keep the consumption level of alcohol static. Thus most brands are beginning to look like volume drivers. Eyeing the exponential growth in the craft beer market Allied Market Research, has published a market research report on Global Beer Market. The study confirms craft beer market has paved a path for the next generation brewers. 

So to keep the craft beer sales on the rise the marketing cliché has played a major role in getting the service or brands in front of buyers. Craft beer manufacturers today need more than a simple ho-hum branding or advertising campaign or a Twitter page followers. Today, brands need to stand out and a little secret to it is creativity. Craft beers are in the front lines of competing with each other for cross –drinkers. 

Thursday, 8 October 2015

Smart Pills transforming the Diagnostics and Healthcare Market

Smart pills are ingestible medical devices consisting of elements such as sensors, cameras, patches and trackers that help in better diagnostics and monitoring. These unique devices can be easily swallowed and offer a non-invasive thorough examination of the gastrointestinal (GI) tract. The smart pills also enables comprehensive health monitoring of various physiological metrics and measuring medication adherence in patients. The below demo clearly indicates how to use the device to monitor your daily medicine intake.



Smart pill technology has revolutionized the field of GI diagnosis. Smart pills are likely to replace conventional diagnostic techniques such as endoscopy and colonoscopy. Capsule endoscopy is regarded as a major technical innovation, influencing investigation and management of various small bowel diseases, esophageal disorders, colonic disorders etc. Capsule endoscopes are designed to provide complete examination of GIT including images of esophagus, stomach, small intestine and large intestine.. The capsule endoscopy segment is gaining a strong foothold in the smart pills market.

The capsule endoscopy is noninvasive and causes minimal discomfort. The magnification obtained, here is of the order 1:8, which is much higher as compared to the conventional endoscopy. Various capsule endoscopes available in the market include small bowel capsule, colon capsule and esophagus capsule endoscopes. Small bowel capsule is the most commonly used capsule endoscope in patients with acute gastrointestinal bleeding or to detect symptoms of active Crohn’s disease (CD).On the other hand, esophagus capsule endoscopes are used to diagnose esophagitis and Barrett’s esophagus. 

Companies today are focusing on exploring the field of gastroenterology. Recent studies by various researchers to develop products have enabled clinicians to obtain clearer & better images of the GI tract which offers new hope for gastrointestinal cancer detection Recently, researchers from Chinese University of Hong Kong, have developed an advanced endoscope known as ‘Tadpole Endoscope (TE), which mimics the movement of tadpoles’. TE is different from existing wireless capsule endoscopes since the presence of a soft tail enables it to be guided around the GI tract remotely by a clinician. This allows for better imaging of the stomach and thereby helping in the accurate location of problems.

Recently in 2014, Given Imaging Ltd, a pioneer of capsule endoscopy received FDA clearance for PillCam COLON. The device provides new modality to ensure clear visualization of the colon in patients following incomplete colonoscopy. According to some recent studies, incomplete colonoscopies occur in approximately 750,000 patients in the United States alone every year. The number is further higher in women due to an increase in past pelvic surgeries. There is a growing demand for such devices among patients having long case history of abdominal surgery or advanced stage of diverticular disease. This non-invasive test enabled by PillCam COLON allows more people to get screened for colorectal cancer, and gives a minimally invasive, radiation-free option. These devices in the market have revolutionized colorectal cancer diagnostics and screening market worldwide. The following infographics shows how the product PillCam COLON works. 



Another key application of smart pills is patient monitoring that includes monitoring of parameters such as pH, temperature, pressure and drug adherence in patients. According to the World Health Organization (WHO) estimate, over 50% of us fail to take medicines correctly, while over 50% of drugs are prescribed or sold inappropriately. This leads to disastrous consequences, resulting in significant complications and deterioration of patient health. The situation aggravates with ageing of patients, since they often require management of one or more chronic conditions with multiple medications. The trend may also cost healthcare providers millions every year. 




To deal with such non-adherence in patients due to various reasons, Proteus Digital Health, Inc. California-based Proteus Digital Health and Otsuka Pharmaceuticals have developed smart pill having an ingestible sensor. The digital pill is first of its kind to be approved by the U.S. Food and Drug Administration (FDA) as an aid to measure medication adherence.  The new drug application accepted by FDA was for an oral tablet that combines Otsuka’s branded antipsychotic Abilify (aripiprazole) with an embedded ingestible sensor device developed by Proteus Digital Health The ingestible device consists of minuscule sensors made of silicon along with metals-magnesium and copper, present in traces. The device gets powered on when the metals come in contact with stomach acids thereby triggering the sensor to generate signals that can be picked up by a disposable bandage-like patch worn by patient. The patch relays information to a mobile phone application. The following link shows how clinicians will use FDA approved digital pill to monitor patients and facilitate effective drug delivery among them. 

With the patient’s consent, the information can be assessed by caregivers and clinicians, thus helping individuals to develop and sustain healthy habits. Furthermore, it enables medical practitioners and doctors to offer more effective, data-driven health-care. The application can track the drug's effects - whether it's been prescribed at the right dosage, or if it simply isn't having any effect on the patient’s body..

The following tweets highlights the promising features of smart pills.
There are many research studies done by market research firms which tracks the current and future market trends along with offering an insight into the key drivers and growth opportunities of the market across major regions. As per a recent report by Allied Market Research, the smart pills technology market would reach $627.1 million, globally, by 2020, registering 21.2% CAGR during the forecast period 2015-2020.

In future, technological advancements to enhance the features of smart pills such as non-invasiveness, patient convenience and real time monitoring would drive their adoption rate in patient monitoring, diagnostic imaging and drug delivery.